Pharmacoinformatic Approach for Sars

نویسندگان

  • Sivakumar
  • Seenivasagam
  • Muthukrishnan
  • Niranjan
چکیده

SARS is a respiratory disease caused by corona virus, it is produced the flu like symptoms and severe bronchial constriction ,alveoli inflammation it’s leads to death fever, myalgia, lethargy, gastrointestinal symptoms, cough, sore throat and other non-specific symptoms. , The rapid transmission and high mortality rate made SARS a global threat for which no efficacious therapy was available and empirical strategies had to be used to treat the patients. New insights into the field of the SARS-CoV genome structure and pathogenesis revealed novel potential anti-Corona virus targets. Several proteins encoded by the SARS-CoV could be considered as targets for therapeutic intervention.pharmacoinformatic approach of SARS gave new opportunities for the development of therapeutics, an extensive analysis of the SARS proteins including modeling of its structure may prove useful in designing a drug for SARS treatment. Further comprehensive work on this protein will leads to a new milestone in SARS research.

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تاریخ انتشار 2002